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Search ARV DDI
Antiretroviral treatment
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Abacavir
Abacavir/Lamivudine
Abacavir/Lamivudine/Zidovudine
Atazanavir (unboosted)
Atazanavir (with Ritonavir or Cobicistat)
Atazanavir/Cobicistat
Bictegravir/Emtricitabine/Tenofovir-AF
Cabotegravir/Rilpivirine LA
Cobicistat
Darunavir (with Ritonavir or Cobicistat)
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Didanosine
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Doravirine/Lamivudine/Tenofovir-DF
Efavirenz
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Ritonavir
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Tenofovir-AF
Tenofovir-DF
Zidovudine
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Comedication or substance you are interested in
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Abacavir
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Inula Racemosa
Iodine
Ipilimumab
Ipratropium Bromide
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Iron Supplements
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Isotrentinoin
Itraconazole
Ivabradine
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Other (Not In The List)
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Solifenacin
Sorafenib
Sotalol
Spectinomycin
Spironolactone
Stanozol
Stavudine
Streptokinase
Streptomycin
Sucralfate
Sufentanil
Sulbactam
Sulfadiazine
Sulfamethoxazole + Trimethoprim
Sulfasalazine
Sulpiride
Sumatriptan
Sunitinib
Tacrolimus
Tadalafil
Tamoxifen
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Tedizolid
Teicoplanin
Tejocote Root (Crataegus Mexicana Or Crataegus Pubescens)
Telaprevir
Telbivudine
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Temazepam
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Terazosin
Terbinafine
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Theophylline
Thiamine (Vitamin B1)
Thiopental
Thioridazine
Thymus Vulgaris
Tiapride
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Trandolapril
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Trastuzumab
Trazodone
Treprostinil
Triamcinolone
Triazolam
Triclabendazole
Trifusal
Trimipramine
Triptorelin
Trospium
Ulipristal
Urokinase
Ursodeoxycholic Acid
Ustekinumab
Valacyclovir
Valeriana Officinalis
Valganciclovir
Valproate
Valpromide
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Vardenafil
Varenicline
Vedolizumab
Vencuronium
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Vigabatrin
Vilanterol
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Vinblastine
Vincristine
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Vinorelbine
Voriconazole
Vorinostat
Vortioxetine
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Xipamide
Zaleplon
Zanamivir
Zidovudine
Ziprasidone
Zoledronic Acid
Zolmitriptan
Zolpidem
Zopiclone
Zosinamide
Zotepine
Zuclopenixol
If this comedication is not in the list this means that there are not reported any cases involving this drug
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Last reported clinical cases between ARVs and comedications
Visited Case
P = Perpetrator
V = Victim
View
ARV involved
Comedication
Clinical Outcome
Liverpool Recommendation
Details
Bictegravir
(V)
Rifabutin
(P)
No unwanted outcome
Nevirapine
(V)
Hypericum perforatum
(P)
Loss of efficacy
Tenofovir-DF
Clarithromycin
(P)
No unwanted outcome
Dolutegravir
Norgestrel
No unwanted outcome
Cobicistat
(P)
Solifenacin
(V)
No unwanted outcome
Cobicistat
(P)
Simvastatin
(V)
No unwanted outcome
Dolutegravir
(V)
Ginkgo biloba
(P)
No unwanted outcome
Cobicistat
(P)
Paroxetine
(V)
Toxicity
Rilpivirine LA
Escitalopram
No unwanted outcome
Efavirenz
(P)
Risperidone
(V)
Loss of efficacy
Dolutegravir
(V)
Garlic
(P)
Loss of efficacy
Cobicistat
(P)
Drospirenone
(V)
No unwanted outcome
Ritonavir
(P)
Vinblastine
(V)
Toxicity
Efavirenz
(V)
Horsetail
(P)
Loss of efficacy
N/A
Lopinavir/Ritonavir
(P)
Terfenadine
(V)
Toxicity
Dolutegravir
(P)
Metformin
(V)
Toxicity
Bictegravir
(V)
Ursodeoxycholic acid
(P)
No unwanted outcome
Bictegravir
Cytisine
No unwanted outcome
Cobicistat
(P)
Ergotamine
(V)
Toxicity
Rilpivirine
(V)
Clarithromycin
(P)
No unwanted outcome
Efavirenz
(P)
Sofosbuvir + Velpatasvir
(V)
No unwanted outcome
Elvitegravir
(V)
Dexamethasone
(P)
No unwanted outcome
Bictegravir
(V)
Brivaracetam
(P)
No unwanted outcome
N/A
Ritonavir
(P)
Levonorgestrel
(V)
Toxicity
Cobicistat
(P)
Red yeast rice (monacolin)
(V)
No unwanted outcome
Dolutegravir
(V)
Eslicabazepine
(P)
No unwanted outcome
Cobicistat
(P)
Amiodarone
(V)
No unwanted outcome
Rilpivirine
(V)
Rifampin
(P)
Loss of efficacy
Cobicistat
(P)
Apixaban
(V)
No unwanted outcome
Cobicistat
(P)
Atorvastatin
(V)
No unwanted outcome
Bictegravir
(V)
Oxcarbazepine
(P)
No unwanted outcome
Cobicistat
(P)
Simvastatin
(V)
Toxicity
Cobicistat
(P)
Silodosin
(V)
No unwanted outcome
Bictegravir
(V)
Oxcarbazepine
(P)
No unwanted outcome
Cobicistat
(P)
Budesonide
(V)
Toxicity
Cobicistat
(P)
Clopidogrel
(V)
No unwanted outcome
Cobicistat
(P)
Atorvastatin
(V)
Toxicity
Cobicistat
(P)
Ticagrelor
(V)
No unwanted outcome
Bictegravir
(V)
Oxcarbazepine
(P)
No unwanted outcome
Raltegravir
Melissa officinalis
No unwanted outcome
N/A
Bictegravir
(V)
Clarithromycin
(P)
No unwanted outcome
Bictegravir
(V)
Voriconazole
(P)
No unwanted outcome
Cobicistat
(P)
Mirtazapine
(V)
No unwanted outcome
Ritonavir
(P)
Anabolic steroids/Androgen agonists
(V)
Toxicity
N/A
Dolutegravir
(V)
Enzalutamide
(P)
No unwanted outcome
Dolutegravir
(V)
Calcium supplements
(P)
Loss of efficacy
Dolutegravir
(V)
Magnesium supplements
(P)
Loss of efficacy
Cobicistat
(P)
Dexamethasone
(V)
Toxicity
Cobicistat
(P)
Atorvastatin
(V)
Loss of efficacy
Bictegravir
(V)
Rifampin
(P)
No unwanted outcome
Darunavir
Melissa officinalis
No unwanted outcome
N/A
Efavirenz
Melissa officinalis
No unwanted outcome
N/A
Ritonavir
(P)
Anabolic steroids/Androgen agonists
(V)
Toxicity
N/A
Ritonavir
(P)
Mycophenolate
(V)
No unwanted outcome
Ritonavir
(P)
Atorvastatin
(V)
No unwanted outcome
Ritonavir
(P)
Epleronone
(V)
Toxicity
Rilpivirine
(V)
Omeprazol
(P)
No unwanted outcome
Cobicistat
(P)
Ergotamine
(V)
Toxicity
Ritonavir
(P)
Apixaban
(V)
No unwanted outcome
Cobicistat
(P)
Atorvastatin
(V)
No unwanted outcome
Ibalizumab
Vincristine
No unwanted outcome
Cobicistat
(P)
Atorvastatin
(V)
No unwanted outcome
Bictegravir
(V)
Mineral supplements
(P)
Loss of efficacy
Dolutegravir
(V)
Mineral supplements
(P)
Loss of efficacy
Ritonavir
(P)
Daclatasvir
(V)
Toxicity
Etravirine
(P)
Tacrolimus
(V)
No unwanted outcome
Nevirapine
(P)
Quetiapine
(V)
Toxicity
Lopinavir/Ritonavir
(P)
Paclitaxel
(V)
Toxicity
Doravirine
(P)
Atorvastatin
(V)
No unwanted outcome
Nevirapine
(P)
Warfarin
(V)
Toxicity
Ritonavir
(P)
Fluticasone
(V)
Toxicity
Cobicistat
(P)
Triamcinolone
(V)
Toxicity
Ritonavir
(P)
Anabolic steroids/Androgen agonists
(V)
Toxicity
N/A
Efavirenz
(V)
Hypericum perforatum
(P)
Loss of efficacy
Efavirenz
(V)
Ginkgo biloba
(P)
Loss of efficacy
Cobicistat
(P)
Nebivolol
(V)
Toxicity
Cobicistat
(P)
Midazolam (oral)
(V)
Toxicity
Cobicistat
(P)
Sildenafil
(V)
Toxicity
Bictegravir
(P)
Metformin
(V)
No unwanted outcome
Ritonavir
(P)
Epleronone
(V)
Toxicity
Doravirine
(V)
Isavuconazole
(P)
No unwanted outcome
Cobicistat
(P)
Rifabutin
(V)
Toxicity
Darunavir
(V)
Enzalutamide
(P)
No unwanted outcome
Tenofovir-AF
(P)
Gentamicin
Toxicity
Bictegravir
(V)
Mineral supplements
(P)
Loss of efficacy
Raltegravir
(V)
Enzalutamide
(P)
No unwanted outcome
Cobicistat
(P)
Voriconazole
(V)
No unwanted outcome
Doravirine
(V)
Omeprazol
(P)
No unwanted outcome
Efavirenz
(P)
Solifenacin
(V)
Loss of efficacy
Cobicistat
(P)
Ecstasy (MDMA)
(V)
Toxicity
Nevirapine
(P)
Desogestrel
(V)
Loss of efficacy
Rilpivirine
Chlorpromazine
No unwanted outcome
Dolutegravir
(P)
Apixaban
(V)
No unwanted outcome
Ritonavir
(P)
Paclitaxel
(V)
Toxicity
Etravirine
(V)
Fluconazole
(P)
Toxicity
Cobicistat
(P)
Paliperidone
(V)
No unwanted outcome
Etravirine
(P)
Apixaban
(V)
Loss of efficacy
Cobicistat
(P)
Clorazepate
(V)
No unwanted outcome
Raltegravir
(P)
Clopidogrel
(V)
No unwanted outcome
Ritonavir
(P)
Triamcinolone
(V)
No unwanted outcome
Dolutegravir
(V)
Valproate
(P)
Loss of efficacy
Cobicistat
(P)
Fluticasone
(V)
No unwanted outcome
Cobicistat
(P)
Alprazolam
(V)
Toxicity
Dolutegravir
(V)
Mineral supplements
(P)
Loss of efficacy
Rilpivirine
(V)
Dexamethasone
(P)
Loss of efficacy
Ritonavir
(P)
Quetiapine
(V)
No unwanted outcome
Cobicistat
(P)
Norgestimate
(V)
No unwanted outcome
Cobicistat
(P)
Aripiprazole
(V)
No unwanted outcome
Cobicistat
(P)
Paliperidone
(V)
No unwanted outcome
Nevirapine
(V)
Dexamethasone
(P)
Loss of efficacy
Cobicistat
(P)
Sildenafil
(V)
Toxicity
Cobicistat
(P)
Atorvastatin
(V)
Toxicity
Darunavir
(V)
Psyllium
(P)
Loss of efficacy
Atazanavir
(V)
Naringin
(P)
Loss of efficacy
N/A
Efavirenz
(V)
Orlistat
(P)
Loss of efficacy
Ritonavir
(P)
Clopidogrel
(V)
No unwanted outcome
Raltegravir
(P)
Ticlopidine
(V)
No unwanted outcome
N/A
Efavirenz
(P)
Carvedilol
(V)
No unwanted outcome
Atazanavir
(V)
Orlistat
(P)
Loss of efficacy
Cobicistat
(P)
Amlodipine
(V)
Toxicity
Tenofovir-AF
(V)
Pemetrexed
(P)
No unwanted outcome
Cobicistat
(P)
Rosuvastatin
(V)
No unwanted outcome
Ritonavir
(P)
Rivaroxaban
(V)
Loss of efficacy
Ritonavir
(P)
Fluticasone
(V)
Toxicity
Cobicistat
(P)
Simvastatin
(V)
Toxicity
Cobicistat
(P)
Quetiapine
(V)
No unwanted outcome
Raltegravir
(V)
Mineral supplements
(P)
Loss of efficacy
Darunavir
(V)
Carbamazepine
(P)
Loss of efficacy
Raltegravir
(V)
Rifampin
(P)
No unwanted outcome
Tenofovir-AF
(V)
Cyclosporine
(P)
No unwanted outcome
Elvitegravir
(P)
Warfarin
(V)
Loss of efficacy
Cobicistat
(P)
Ergotamine
(V)
Toxicity
Cobicistat
(P)
Ranolazine
(V)
Toxicity
Cobicistat
(P)
Simvastatin
(V)
Toxicity
Cobicistat
(P)
Vinblastine
(V)
Toxicity
Cobicistat
(P)
Duloxetine
(V)
No unwanted outcome
Cobicistat
(P)
Fluticasone
(V)
Toxicity
Ritonavir
(P)
Rifabutin
(V)
No unwanted outcome
Ritonavir
(P)
Nebivolol
(V)
No unwanted outcome
Cobicistat
(P)
Red yeast rice (monacolin)
(V)
No unwanted outcome
Cobicistat
(P)
Quetiapine
(V)
Toxicity
Ritonavir
(P)
Solifenacin
(V)
Toxicity
Cobicistat
(P)
Paclitaxel
(V)
No unwanted outcome
Cobicistat
(P)
Quetiapine
(V)
No unwanted outcome
Raltegravir
(V)
Eslicabazepine
(P)
No unwanted outcome
Cobicistat
(P)
Tacrolimus
(V)
No unwanted outcome
Bictegravir
(V)
Eslicabazepine
(P)
No unwanted outcome
Raltegravir
(V)
Dietary supplements
(P)
Loss of efficacy
N/A
Ritonavir
(P)
Atorvastatin
(V)
No unwanted outcome
Dolutegravir
(V)
Oxcarbazepine
(P)
No unwanted outcome
Cobicistat
(P)
Quetiapine
(V)
No unwanted outcome
Raltegravir
(V)
Mineral supplements
(P)
Loss of efficacy
Cobicistat
(P)
Triamcinolone
(V)
Toxicity
Tenofovir-AF
(V)
Primidone
(P)
No unwanted outcome
Cobicistat
(P)
Quetiapine
(V)
No unwanted outcome
Cobicistat
(P)
Quetiapine
(V)
Toxicity
Cobicistat
(P)
Tamsulosin
(V)
No unwanted outcome
Rilpivirine
Methadone
Toxicity
Cobicistat
(P)
Red yeast rice (monacolin)
(V)
No unwanted outcome
Raltegravir
(V)
Dietary supplements
(P)
Loss of efficacy
N/A
Darunavir
(V)
Tejocote root (Crataegus mexicana or Crataegus pubescens)
(P)
Loss of efficacy
N/A
Cobicistat
(P)
Paliperidone
(V)
No unwanted outcome
Raltegravir
(P)
Melphalan
(V)
No unwanted outcome
N/A
Rilpivirine
(V)
Omeprazol
(P)
No unwanted outcome
Dolutegravir
(V)
Mineral supplements
(P)
No unwanted outcome
Cobicistat
(P)
Alprazolam
(V)
No unwanted outcome
Atazanavir
(V)
Omeprazol
(P)
No unwanted outcome
Cobicistat
(P)
Atorvastatin
(V)
No unwanted outcome
Cobicistat
(P)
Atorvastatin
(V)
No unwanted outcome
Cobicistat
(P)
Bosentan
(V)
Toxicity
Cobicistat
(V)
Bosentan
(P)
Loss of efficacy
Lopinavir/Ritonavir
(P)
Clopidogrel
(V)
Loss of efficacy
Efavirenz
(P)
Ticagrelor
(V)
Loss of efficacy
Rilpivirine
(V)
Omeprazol
(P)
No unwanted outcome
Dolutegravir
(V)
Oxcarbazepine
(P)
No unwanted outcome